GET THE APP

All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.

Abstract

Evalution of Anti-Inflammatory Activity of Tulsi Stem (Ocimum Sanctum Linn.) by Using Carrageenan-Induced Paw Edema Model Care

Aanchal Gwari*, Arvind Negi and Manish Mishra

Ocimum sanctum (L.) is commonly used as a herbal remedy for various ailments. But the scientific basis for its medicinal use is unknown, especially in pain and inflammation. Therefore, the present study aimed to investigate the anti-inflammatory effects of Ocimum sanctum stems in laboratory animals. Inflammation remains an area of great research interest, possibly due to the unavailability of a safer and more effective anti-inflammatory agent. This has led to an increased demand for natural products with anti-inflammatory activity, which has fewer side effects. Non-Steroidal Anti- Inflammatory Drugs (NSAIDs) such as indomethacin are used to treat inflammation, fever, and pain. However, NSAIDs cause gastric damage as a major adverse reaction. Methanol, ethanol extract from O. sanctum stem was used to study the acute effect of inflammation in rats using a carrageenan-induced paw edema model in wistar albino rats. The ethanolic extract of O. sanctum showed more impact at doses of 200 mg/kg of body weight at the fourth hour of the study shown dose-dependent and anti-inflammatory activity in acute inflammation (carrageenan-induced hind paw edema, p<0.05)) of inflammation. Hence, present investigation established some pharmacological evidences to support the folklore claim that Ocimum sanctum is used as anti-inflammatory agent.


HTML PDF

Manuscript Submission

Submit your manuscript at  https://www.scholarscentral.org/submissions/international-pharmacy.html


Google scholar citation report
Citations : 938

International Journal of Pharmacy received 938 citations as per google scholar report

International Journal of Pharmacy peer review process verified at publons
Indexed In
  • CAS Source Index (CASSI)
  • HINARI
  • Google Scholar
  • The Global Impact Factor (GIF)
  • Polish Scholarly Bibliography (PBN)
  • Cosmos IF
  • Open Academic Journals Index (OAJI)
  • Directory of Research Journal Indexing (DRJI)
  • EBSCO A-Z
  • International committee of medical journals editors (ICMJE)
  • Scientific Indexing Services (SIS)
  • Scientific Journal Impact Factor (SJIF)
  • Euro Pub
  • Eurasian Scientific Journal Index
  • Root indexing
  • International Institute of Organized Research
  • InfoBase Index
  • International Innovative Journal Impact Factor