The pharmaceutical industry and health professionals are experiencing a deficit in an innovation, especially in the finding new ways of patient targeting. Innovative advances in drug targeting discovery and includes Ethno pharmacology, biological function and holistic targeting provides an integral review and analysis of health, pathogenesis of disease and medicine effect and examine possible reasons behind the present catastrophe in drug discovery. The benefits of biological response and pharmacogenomics outcome and proponent the extension from disease centric discovery to patient-centric therapeutics involving chronobiotics, multi-target, whole systems approach. It also lays the path revive pharmaceutical revolution through a disciplined resurgence of antique medicine, appealing open innovation models and association trusted public-private partnerships. With impressive advances made in the evolution of biometrically relevant implements and technologies, the demand is higher and right now for a recommence commitment towards patients’ satisfaction. By absorbing real-life samples and state of the art reviews and cost effectiveness of product, this novel targeting methods provides profitable acumen into the learning and advancement strategies for healthcare professionals, academicians and learners in the pharmacy sciences and clinical practice.
Keywords: Drug discovery, Patient targeting discovery, Pharmacogenomics, Innovative approach, Network pharmacology, Holistic lifestyle, Chronotherapeutic.
Abbreviations: NP: Network Pharmacology; ABP: Ambulatory Blood Pressure; FDA: Food and Drug Administration; IBD: Inflammatory Bowel Syndrome; CD: Crohn’s Disease; RA: Rheumatoid Disease; SCD: Sickle Cell Disease; RBC: Red Blood Cell; NAD: Nicotinamide Adenine; Dinucleotide NADH: Nicotinamide Adenine Dinucleotide Hydrogen; RGP: Rigid Gas Permeable; Ortho-K: Orthokeratology; CRT: Corneal Refractive Therapy; GVSS: Gentle Vision Shaping System GVSS; ADFs: Abuse-Deterrent Formulations; PFDDM: Patient Focused Drug Development Meeting; NP: Network Pharmacology; KEGG: Kyoto Encyclopedia of Genes and Genomes; HDN: Human Disease Network; MDN: Metabolic; Disease Networks; PDN: Phenotypic Disease Networks; HSDN: Human Symptom Disease Network; DTN: Drug Target Network; API: Active Pharmaceutical Ingredient.
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