GET THE APP

All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.

Abstract

VALIDATED SPECTROPHOTOMETRIC AND SPECTROFLUORIMETRIC METHODS FOR THE DETERMINATION OF PREGABALIN IN ITS PURE AND DOSAGE FORMS USING EOSIN

Mohammed I. Walash, N. El-Enany and H. Askar*

Two sensitive spectrophotometric and spectrofluorimetric methods were developed for determination of pregabalin (PGB) in its pure and pharmaceutical dosage forms. For spectrophotometric method (Method I), absorbance value of a binary complex with eosin was measured at 550 nm at pH 3.5. The absorbance-concentration plot was rectilinear over the range of 4-80 μg mL-1. For spectrofluorimetric method (Method II), the decreasing in the fluorescence intensity of the native fluorescence of eosin was measured at 544 nm after excitation at 304 nm at the same pH. The fluorescence-concentration plot was rectilinear over the range of 0.05-1 μg mL-1. Statistical comparison of the results with those of the reference method indicated that there was no significant difference between the two methods respectively.


PDF

Manuscript Submission

Submit your manuscript at  https://www.scholarscentral.org/submissions/international-pharmacy.html


Google scholar citation report
Citations : 938

International Journal of Pharmacy received 938 citations as per google scholar report

International Journal of Pharmacy peer review process verified at publons
Indexed In
  • CAS Source Index (CASSI)
  • HINARI
  • Google Scholar
  • The Global Impact Factor (GIF)
  • Polish Scholarly Bibliography (PBN)
  • Cosmos IF
  • Open Academic Journals Index (OAJI)
  • Directory of Research Journal Indexing (DRJI)
  • EBSCO A-Z
  • International committee of medical journals editors (ICMJE)
  • Scientific Indexing Services (SIS)
  • Scientific Journal Impact Factor (SJIF)
  • Euro Pub
  • Eurasian Scientific Journal Index
  • Root indexing
  • International Institute of Organized Research
  • InfoBase Index
  • International Innovative Journal Impact Factor