SYNTHETIC CURCUMINOID COMPOUNDS: AN APPRAISAL OF IN VITRO ANTIOXIDANT ACTIVITY

Jyotsana Sharma, Anurag Singh Chauhan

The present study aimed at synthesizing curcumin and some related curcuminoid compounds and thereafter evaluation of these compounds for possible antioxidant activity. Previously synthesized and identified Curcumin and curcuminoid compounds were taken for the study. Antioxidant potential of the compounds were investigated. Total antioxidant activity, reducing power assay, nitric oxide scavenging activity, hydrogen and DPPH radical scavenging activity were performed to evaluate the antioxidant potential of these compounds in vitro. The IC₅₀ values in DPPH model were also calculated. The results of the study revealed potential antioxidant activities of the evaluated compounds.