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Abstract

SYNTHESIS OF A PRODRUG OF ACECLOFENAC AND ITS METHOD DEVELOPMENT BY UV-SPECTROSCOPY

Niti Bhardwaj, P. Ahuja, Farah Iram, Asif Husain*

An ester-based prodrug (2) of aceclofenac was synthesized using N-hydroxymethylsuccinimide (1) as promoiety and its structure established on the basis of IR, NMR and Mass spectral data. An analytical, rapid, cost-effective and accurate method using UV-spectroscopy has been developed for the synthesized prodrug (2). The value of R square obtained shows that the developed method is rapid, easy and precise.


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