SYNTHESIS, CHARACTERIZATION AND BIOLOGICAL EVALUATION OF SOME NEW CHALCONES

Padma R*, Aruna R, E Mounika, I. Manjusha and B Soniya

In this work, new substituted chalcones (1-6) were prepared by reacting 4-Methoxy acetophenone with the corresponding substituted aromatic aldehydes in the presence of methanolic potassium hydroxide solution at room temperature.Some of the compounds synthesized from methoxy, chloro, Dimethlyamino derivatives showed moderate antibacterial activity at 0.2% concentration. These compounds may show more antibacterial activity at higher concentrations.