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Abstract

SYNTHESIS AND BIOLOGICAL INVESTIGATION OF SOME NOVEL SULFONAMIDE DERIVATIVES CONTAINING BENZIMIDAZOLE MOIETY

Shipra Bhati* and Pratibha Bidawat

A new class of potentially biological active sulfonamide derivatives containing Benzimidazole moiety has been synthesized. The newly synthesized compounds were characterized by spectroscopic methods and elemental analysis. Further, the synthesized compounds were evaluated for antibacterial and antioxidant activity. Their antibacterial activity was assigned using the conventional cup plate method and antioxidant activity was assessed using 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging method. The synthesized compounds exhibited significant antibacterial and antioxidant activities compared to standard compounds.


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