All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.



Anupama Puntambekar*, Amrita Bajaj, Pranita Savardekar

The aim of the present study was to design and develop a suitable intranasal spray formulation of surface modified liposomes to improve the concentration of anti-psychotic drug into the brain tissue for therapy of schizophrenia. Liposomal spray solution was optimized; particle size, zeta potential and polydispersity index were measured using Malvern Zetasizer. Morphology of liposomal spray droplets was examined using scanning electron microscopy. Drug diffusion studies were performed and drug diffused was estimated using UV spectroscopic analysis. Stable liposomal spray was formulated. The optimized liposomal spray showed uniform vesicles in the size range 155-170 nm and zeta potential of optimized formulation was found to be 29.77. Surface coating was done using chitosan solution in glacial acetic acid and evaluated. Intranasal surface modified liposomal spray exhibited higher deposition in brain tissues compared to conventional solution after intranasal and intramuscular administration indicating potential for nose to brain targeting. Thus nasal drug delivery offers a viable alternative to oral and injectable routes of administration.

scan code pharma scholars

Manuscript Submission

Submit your manuscript at  Online Submission System

Google scholar citation report
Citations : 1101

International Journal of Pharmacy received 1101 citations as per google scholar report

International Journal of Pharmacy peer review process verified at publons
Indexed In
  • CAS Source Index (CASSI)
  • Google Scholar
  • The Global Impact Factor (GIF)
  • Polish Scholarly Bibliography (PBN)
  • Cosmos IF
  • Open Academic Journals Index (OAJI)
  • Directory of Research Journal Indexing (DRJI)
  • International committee of medical journals editors (ICMJE)
  • Scientific Indexing Services (SIS)
  • Scientific Journal Impact Factor (SJIF)
  • Euro Pub
  • Eurasian Scientific Journal Index
  • Root indexing
  • International Institute of Organized Research
  • InfoBase Index
  • International Innovative Journal Impact Factor