GET THE APP

All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.

Abstract

Structure Based Drug Design and Synthesis of Ibuprofen analogs as Cox Inhibitors

T. Umema Naaz1*, Shaheen Begum2, Nameera Jabeen2, Yerragunta Vishwanadham 1

Cyclooxygenase-2 (COX-2) is one of the important targets for treatment of inflammation related diseases. Structure based drug design was carried out for about 1000 molecules and then molecules having good interactions with 3NT1 protein were synthesized. According to the results of molecular docking, the synthesized novel ibuprofen schiff bases derivatives have selective COX-2 inhibition. In conclusion, the newly synthesized ibuprofen derivatives can be used in model in vivo studies.


PDF

Manuscript Submission

Submit your manuscript at  https://www.scholarscentral.org/submissions/international-pharmacy.html


Google scholar citation report
Citations : 938

International Journal of Pharmacy received 938 citations as per google scholar report

International Journal of Pharmacy peer review process verified at publons
Indexed In
  • CAS Source Index (CASSI)
  • HINARI
  • Google Scholar
  • The Global Impact Factor (GIF)
  • Polish Scholarly Bibliography (PBN)
  • Cosmos IF
  • Open Academic Journals Index (OAJI)
  • Directory of Research Journal Indexing (DRJI)
  • EBSCO A-Z
  • International committee of medical journals editors (ICMJE)
  • Scientific Indexing Services (SIS)
  • Scientific Journal Impact Factor (SJIF)
  • Euro Pub
  • Eurasian Scientific Journal Index
  • Root indexing
  • International Institute of Organized Research
  • InfoBase Index
  • International Innovative Journal Impact Factor