Mahasin Aliasa, Farah Saadoon, Maha Faisal, Nibras Mohammed, Caroline Shaker
Mixed ligands complexes have been prepared by reaction of Sodium [5-(p-nitrophenyl)-'4-phenyl-1,2,4-traizole-3- dithiocarbamato hydrazide] (L1) and 1,10-phenanthroline (L2) with Fe(III) and Mn(II) ions. The newly prepared complexes were isolated and characterized by FT-IR and UV-Vis spectroscopy, C.H.N., FAA technique, in addition to magnetic susceptibility and conductivity measurements. The nature of bonding between the metal ion and the donor atoms of the ligands were demonstrated by calculating of the ligand field parameters using suitable Tanaba- Sugano diagrams. Cytotoxic effect of the prepared complexes were evaluated against Hep-2 cell line using different concentrations (3000, 1500, 750 and 375 μg/ml) respectively in an exposure time 72 hrs comparing this effect with control positive Cis-Pt as reference drug.
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