GET THE APP

All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.

Abstract

PRELIMINARY PHYTOCHEMICAL SCREENING, IN VITRO ANTIOXIDANT AND CYTOTOXIC ACTIVITY OF FIVE DIFFERENT EXTRACTS OF WITHANIA SOMNIFERA ROOT

Mohammad Shahriar*, Abu Nizam Md Bahar, Md. Ismail Hossain, Sadika Akhter, Md. Aminul Haque and Mohiuddin Ahmed Bhuiyan

Current investigation aimed to assess the phytochemical screening, free radical scavenging potential and cytotoxic activity of the root extracts of Withania somnifera (Ashwagandha). Phytochemical screening revealed the presence of phenol, flavonoid, tannin, saponin, alkaloid, glycoside and carbohydrate. In evaluation, methanol, ethanol, chloroform, pet-ether and n-hexane extract of the root powder was prepared and screened for in-vitro antioxidant activities by 1, 1-diphenyl-2-picrylhydrazyl (DPPH) free radical scavenging activity where chloroform, pet-ether and methanol extract of Withania somnifera showed noticeable effect in the DPPH scavenging assay. All five extracts were subjected to brine shrimp lethality bioassay for possible cytotoxicity. Concentration dependent increment in percent mortality of Brine Shrimp nauplii produced by the ethanol extract of Withania somnifera indicates the presence of cytotoxic principles in these extractives. 


PDF
scan code pharma scholars

Manuscript Submission

Submit your manuscript at  Online Submission System


Google scholar citation report
Citations : 1101

International Journal of Pharmacy received 1101 citations as per google scholar report

International Journal of Pharmacy peer review process verified at publons
Indexed In
  • CAS Source Index (CASSI)
  • HINARI
  • Index Copernicus
  • Google Scholar
  • The Global Impact Factor (GIF)
  • Polish Scholarly Bibliography (PBN)
  • Cosmos IF
  • Open Academic Journals Index (OAJI)
  • Directory of Research Journal Indexing (DRJI)
  • EBSCO A-Z
  • OCLC- WorldCat
  • MIAR
  • International committee of medical journals editors (ICMJE)
  • Scientific Indexing Services (SIS)
  • Scientific Journal Impact Factor (SJIF)
  • Euro Pub
  • Eurasian Scientific Journal Index
  • Root indexing
  • International Institute of Organized Research
  • InfoBase Index
  • International Innovative Journal Impact Factor
  • J-Gate