GET THE APP

All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.

Abstract

PRECLINICAL BLOOD CHEMISTRY SAFETY PROFILE STUDIES OF �??ROHITAKARISTA�?� ON THE KIDNEY FUNCTION AFTER CHRONIC ADMINISTRATION TO MALE SPRAGUE-DAWLEY RATS

Md. Arif Hasan, Md. Rakib Hasan*, Mohammad Jashim Uddin, Gulshanara Begum, Nawfel Abdullah, Md. Moklesur Rahman Sarker, Mohammed Motaher Hossain Chowdhury and M. S. K. Choudhuri

Rohitakarista (RHT) is an Ayurvedic preparation used as a traditional medicine in the treatment of splenomegaly. To find out the effect of chronic administration of RHT on serum blood chemistry profile, it was administered chronically to the male Sprague-Dawley rats at a dose of 40 ml/kg for 28 days. In this study, the albumin content was decreased (9.17 %) in RHT treated male rats and it was statistically significant (p=0.047), the globulin content was highly significantly (p=0.012) increased (53.10 %) as a result the decrease (43.18%) in the Albumin / Globulin (A/G) ratio was statistically highly significantly different from their corresponding control values (p=0.005). There were a statistically very highly significant (p=0.001) decrease of blood urea nitrogen (BUN) level (23.97%) and BUN/Creatinine ratio (21.62 %). It was observed that there was a 15.0% decrease in serum uric acid content of RHT treated male rats in comparison to their control male rats which was also statistically significant (p=0.049).


PDF
scan code pharma scholars

Manuscript Submission

Submit your manuscript at  Online Submission System


Google scholar citation report
Citations : 1101

International Journal of Pharmacy received 1101 citations as per google scholar report

International Journal of Pharmacy peer review process verified at publons
Indexed In
  • CAS Source Index (CASSI)
  • HINARI
  • Index Copernicus
  • Google Scholar
  • The Global Impact Factor (GIF)
  • Polish Scholarly Bibliography (PBN)
  • Cosmos IF
  • Open Academic Journals Index (OAJI)
  • Directory of Research Journal Indexing (DRJI)
  • EBSCO A-Z
  • OCLC- WorldCat
  • MIAR
  • International committee of medical journals editors (ICMJE)
  • Scientific Indexing Services (SIS)
  • Scientific Journal Impact Factor (SJIF)
  • Euro Pub
  • Eurasian Scientific Journal Index
  • Root indexing
  • International Institute of Organized Research
  • InfoBase Index
  • International Innovative Journal Impact Factor
  • J-Gate