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Abstract

Potential of Floating Drug Delivery System as an Innovation.

Riffat Latif, Irum Latif, Zulcaif Ahmad, Iftikhar Khan.

The current research related to the formulation of the floating matrix tablets planned to enhance the drug bioavailability, extend the gastric residence time and reduce the side effects of irritating drugs, which are attained after oral administration. Gum arabic, sodium alginate, carrageenan, corn starch, gum guar, hydroxypropyl methylcellulose (HPMC), and polyacrylates were different types of matrix-forming polymers studied. As the type of matrix former the relative importance of drug diffusion, polymer swelling tablet erosion for the resulting release patterns varied significantly. The tablets eroded upon contact with the release medium. The purpose of this article is to evaluate modern technology used in the development of floating drug delivery system as well as summarizes the applications the advantages and disadvantages, characterization, estimation methods and future potential, principle of floating drug delivery system for floating tablets.


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