GET THE APP

All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.

Abstract

NEW ANALYTICAL METHOD DEVELOPMENT AND VALIDATION FOR THE ESTIMATION OF GEMFIBROZIL IN BULK AND PHARMACEUTICAL FORMULATION BY RP-HPLC

*A. Sushma, K. Harinadha Babu and G. Vijay Kumar

A simple, specific and accurate reverse phase high performance liquid chromatographic method was developed for
the determination Gemfibrozil in bulk and pharmaceutical dosage form. The column used was Agilent Zorbax C8
(150 ×4.6mm, 5μ) in gradient mode, with mobile phase containing Solvent-A: phosphate buffer adjusted the pH-
3.0 with orthophosphoric acid Solvent-B: Methanol the flow rate was 1.5 mL/ min and eluents was monitored at 276
nm. The retention time Gemfibrozil was 5.158 min, respectively. The linearity for Gemfibrozil was in the range of
30-450 μg/ml respectively. The recovery of Gemfibrozil was found to be 99.5%, respectively. The proposed method
was validated and successfully applied to the estimation of Gemfibrozil in capsule dosage form.
 


PDF

Manuscript Submission

Submit your manuscript at  https://www.scholarscentral.org/submissions/international-pharmacy.html


Google scholar citation report
Citations : 938

International Journal of Pharmacy received 938 citations as per google scholar report

International Journal of Pharmacy peer review process verified at publons
Indexed In
  • CAS Source Index (CASSI)
  • HINARI
  • Google Scholar
  • The Global Impact Factor (GIF)
  • Polish Scholarly Bibliography (PBN)
  • Cosmos IF
  • Open Academic Journals Index (OAJI)
  • Directory of Research Journal Indexing (DRJI)
  • EBSCO A-Z
  • International committee of medical journals editors (ICMJE)
  • Scientific Indexing Services (SIS)
  • Scientific Journal Impact Factor (SJIF)
  • Euro Pub
  • Eurasian Scientific Journal Index
  • Root indexing
  • International Institute of Organized Research
  • InfoBase Index
  • International Innovative Journal Impact Factor