IN VITRO ASSESSMENT OF ANTIARTHRITIC ACTIVITY OF SPHAERANTHUS AMARANTHOIDES BURM F.

Gayatri S*, Uma Maheswara Reddy C, Chitra K

Present study was done to assess the in vitro antiarthritic activity of the plant Sphaeranthus amaranthoides Burm F (Asteracea). Four different extract of increasing polarity namely petroleum ether, chloroform, ethyl acetate and methanol were prepared. Antiarthritic potential of the plant was assessed by two methods namely, effect on protein denaturating and effect on membrane stabilization. The results indicated that by both the methods ethyl acetate extract was having highest activity and the activity was comparable with that of standard, diclofenac sodium.