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Abstract

FORMULATION AND EVALUATION OF GASTRORETENTIVE FLOATING TABLETS OF FAMOTIDINE

Brajendra singh Rajpoot

The purpose of this investigation was to prepare a gastro retentive drug delivery system of famotidine. Floating tablets of famotidine were prepared by using two different grades of HPMCK4M and HPMCK100M by effervescent technique; these HPMCK have gel-forming properties. The floating tablets were evaluated for weight variation, hardness, friability, drug content. All prepared tablet showed good in vitro buoyancy. 


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