GET THE APP

All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.

Abstract

EVALUATION OF SOLASODINE FROM THE LEAVES OF SOLANUM MAURITIANUM SCOP. BY HPTLC

Jayakumar K and Murugan K*

Solanum mauritianum Scop. is an exotic tree Solanum species of South America. High performance thin layer chromatography method was formulated in S. mauritianum to identify the major alkaloid fractions. Optimal extraction of solasodine includes refluxing with 2.5N methanolic hydrochloric acid, precipitation and extraction using non-polar solvent system. Ideal and prominent bands were obtained on HPTLC silica gel plates using chloroform (9.3): methanol (0.7 v/v) solvent system at 0.32±0.06 Rf. and visualized with anisaldehyde-sulphuric acid. The resulted and derivatized plates were scanned at 530 nm for densitometric analysis. The method was found linear (r2 = 0.9978) in a wide range (20-2000 ng/ spot), accurate (88.2-101.4%), precise (% RSD < 2.88), robust (% RSD < 3.48) and specific. The LOD and LOQ of the method was found as 14 and 44 ng/spot, respectively indicating sensitive enough to analyze minute amount of solasodine in multi-component extract. The method was applied for analysis of solasodine content in samples of S. mauritianum.


PDF

Manuscript Submission

Submit your manuscript at  https://www.scholarscentral.org/submissions/international-pharmacy.html


Google scholar citation report
Citations : 938

International Journal of Pharmacy received 938 citations as per google scholar report

International Journal of Pharmacy peer review process verified at publons
Indexed In
  • CAS Source Index (CASSI)
  • HINARI
  • Google Scholar
  • The Global Impact Factor (GIF)
  • Polish Scholarly Bibliography (PBN)
  • Cosmos IF
  • Open Academic Journals Index (OAJI)
  • Directory of Research Journal Indexing (DRJI)
  • EBSCO A-Z
  • International committee of medical journals editors (ICMJE)
  • Scientific Indexing Services (SIS)
  • Scientific Journal Impact Factor (SJIF)
  • Euro Pub
  • Eurasian Scientific Journal Index
  • Root indexing
  • International Institute of Organized Research
  • InfoBase Index
  • International Innovative Journal Impact Factor