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Abstract

EVALUATION OF ANALGESIC AND ANTI INFLAMMATORY ACTIVITIES OF MOMORDICA CHAIRANTIA

Sri Ramachandra M1*, Srinivasa Rao Avanapu1 and S Shobha Rani

The aim of the present study was to evaluate the Analgesic & anti inflammatory activities of the Momordica
charantia extract. Momordica chirantia (MC) is a herbal medicine traditionally applied to treat so many diseases and
disorders. In the evaluation of analgesic activity the model used was Eddy’s hot plate method in which the animals
treated with Momordica charantia and standard Pentazocin has significantly decreased the Hot plate-induced
writhing and licking responses when compared with control group animals. The anti – inflammatory activity was
screened by Carageenan induced paw edema model in which the animals treated with testing drug and standard
Indomethacin has significantly reduced the inflammation when compared with carageenan induced inflammatory
positive control group animals. So we can conclude that the extract of Momordica charantia has the analgesic and
anti inflammatory activities.


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