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Abstract

COMPARISON STUDIES OF UNCOATED & ENTERIC COATED ASPIRIN FORMULATIONS

K. Gouthami, M. Raghavendra Praneeth, Ch. Madhu Sudan, C. Vandhit Reddy, Roopa Patel, Sarojini N, AS Rao and V. Lokeswara Babu

Aspirin is belonging to the class of NSAID having analgesic, antipyretic, anti-inflammatory and antiplatelet activity at regular normal doses. At higher doses it causes gastrointestinal ulcers, stomach bleeding etc. This effect of aspirin can be minimized by preventing the drug exposure to the gastric region which is achieved by using enteric coating of the aspirin tablet. The present study involves comparison of physical evaluation of uncoated tablets with that of enteric coated tablets of Aspirin.


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