Jagatheesh K, Pavankumar P, Elangovan N, Padmavathi P, Swathi D and Mary Tryphena
Proteomics is a relatively new approach for understanding the pathology and pathogenesis of various diseases. It has also been used for characterizing the modifications in protein expression during the development of diseases. Proteomics is defined as a scientific approach used to elucidate all protein species within a cell or tissue, and many researchers are taking advantage of proteomic technology to elucidate protein changes between healthy and diseased states. Animal model plays an important role in the proteomics technology to find out biomarkers, for diagnosis, prognosis and treatment of various diseases. There are several animal models used in proteomic studies they are Caenorhabditis elegans (worm), Drosophila melanogaster (fly), Mus musculus (mouse) and Canine. This review shows several applications of animal models in proteomics.
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