ANTIPYRETIC ACTIVITY OF THE PLUMERIA RUBRA LEAVES EXTRACT

Vimlesh Misra, Sheikh Mubeen Uddin, Vivek Srivastava and Umashankar Sharma

Antipyretic effect of ethanolic extract of the leaf of plumeria rubra was investigated. Intraperitoneal administration of boiled milk at a dose 0.5 ml/kg body weight in albino rabbit leads to pyrexia. Intraperitoneal (i. p. route) administration of ethanolic extract of the leaf of plumeria rubra at a dose 200mg/kg body weight were shown significantly reduce the elevated body temperature of rabbit which was compared with aspirin (Standard Drug) and solvent used.