GET THE APP

All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.

Abstract

ANTI-PSYCHOTIC EFFECT OF AQUEOUS LEAVES EXTRACT OF MORUS ALBA IN ANIMAL MODELS

Girish P. Laddha and G. Vidyasagar

There are number of patients suffering from of psychiatric condition such as depression, anxiety, schizophrenia, migraine, anti-impulsivity, cognition. Serotonin is the most important neurotransmitters that have been implicated in etiology of number of these psychiatric conditions. Ethyl acetate soluble fraction and insoluble of leaves extracts of morus Alba was carried out on different in-vitro methods. Laboratory animals were given lithium sulphate to causes serotonin blockage from serotonergic neurons. They were treated with different higher concentration clozapine (active comparator) and EASF and EAISF then the psychotic symptoms were monitored to see which group exhibited the best response. The highest dose extract (100mg/kg) was comparable to clozapine in lowering psychotic behavior characterized by head twitches, stereotypy and 5-hydroxytryptophan potention hence both morus Alba and clozapine can be used to treat psychosis induced by amphetamine. The anti-psychotic effect of morus alba leaves may be in dose graded fashion.


PDF

Manuscript Submission

Submit your manuscript at  https://www.scholarscentral.org/submissions/international-pharmacy.html


Google scholar citation report
Citations : 938

International Journal of Pharmacy received 938 citations as per google scholar report

International Journal of Pharmacy peer review process verified at publons
Indexed In
  • CAS Source Index (CASSI)
  • HINARI
  • Google Scholar
  • The Global Impact Factor (GIF)
  • Polish Scholarly Bibliography (PBN)
  • Cosmos IF
  • Open Academic Journals Index (OAJI)
  • Directory of Research Journal Indexing (DRJI)
  • EBSCO A-Z
  • International committee of medical journals editors (ICMJE)
  • Scientific Indexing Services (SIS)
  • Scientific Journal Impact Factor (SJIF)
  • Euro Pub
  • Eurasian Scientific Journal Index
  • Root indexing
  • International Institute of Organized Research
  • InfoBase Index
  • International Innovative Journal Impact Factor