ANTIMICROBIAL AND ANTIINFLAMMATORY ACTIVITIES OF SOME NOVEL TRIAZOLOTHIADIAZOLES

J. Subbarao*, S. Vidhyadhara, N. Srinivasulu

A novel series of 1,2,4-triazolo [ 3,4-b] [ 1,3,4 ] thiadiazoles were prepared by treating 4-amino -3-substituted -5- mercapto-1,2,4-triazoles with 2-amino-4-(substituted phenyl)-3-carboethoxy benzopyron. Their chemical structures were confirmed by means of spectral data IR, 1H NMR and Elemental analysis. All the synthesized compounds were screened for antimicrobial activity and anti-inflammatory activities. Some of the synthesized compounds have shown very good antimicrobial and anti-inflammatory activities.