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Abstract

ANTIDIABETIC ACTIVITY OF ETHANOLIC & AQUEOUS EXTRACT OF AERIAL PART OF THESPESIA LAMPAS (CAV) DALZ AND GIBS ON STREPTOZOTOCIN INDUCED DIABETIC RATS

Syed Mujtaba Ahmed, Anil Middha, Mohammed Omer, D. Ramakrishna

The study evaluates antidiabetic activity of ethanolic & aqueous extract of aerial part of Thespesia.lampas on streptozotocin induced diabetes in rats. Ethanol & Aqueous extract were prepared by soxhlet & maceration process respectively. Antidiabetic activity of the aerial part of the extract at dose 200mg/kg in STZ (i.p 65mg/kg body weight) induced diabetic rats. The study also included the estimation of different biochemical parameters on STZ induced diabetes. The reduced blood glucose levels was statistically significant (P<0.05) in the dose of 200mg/kg of ethanol and aqueous leaf extract when compared with control. The results exhibited potent antihyperglycemic activity in normal and STZ induced diabetic rats so it might be useful in the treatment of diabetes.


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