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Analytical Methods of Six FDA Approved Molecular Entities Used for the Treatment of Non-Small Cell Lung Cancer: A Concise Review

Sajan Das, Sumaiya Huque, Md. Rafi Anwar, Md. Zobayer Hossain Gorapi, Sayeeda Fahmee Chowdhury, Mohammad Shahriar*

Analytical method development and validation are continuous inter-dependent tasks associated with research and development, quality control and quality assurance departments as they help to understand the critical process parameters and to minimize their influence on accuracy and precision. Standard and analytical procedures of anticancer drug may not be available in pharmacopeias. The time and effort that are put into developing scientifically sound, robust, and transferrable analytic methods should be aligned with the drug development stage. Therefore it becomes necessary to develop and validate new analytical methods for such drugs. In this review the methods for the analysis of such recently approved new molecular entities in various matrices are presented. This review helps in understanding the further need for the development of analytical methods for the estimation of such drugs.

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