ANALGESIC AND ANTI-INFLAMMATORY ACTIVITY OF ETHANOLIC AND AQUEOUS WHOLE PLANT EXTRACT OF ASYSTASIA GANGETICA

Mohd Mudassir Hussain*, Vinesh Kumar, G Jeyabalan

In the present study ethanolic and aqueous whole plant extract of Asystasia gangetica was investigated for analgesic and anti-inflammatory activity. Analgesic activity was determined by two different methods (tail immersion & hot plate) & anti-inflammatory activity was determined by three different methods (carrageenan, formalin induced paw edema & cotton pellet granuloma) at dose 200 & 400mg/kg b.wt in experimental animals using diclofenac sodium, tramadol, Indomethacin as reference drugs. In all the animals models the results obtained were statistically significant (P<0.05) in comparison to control. The results obtained indicate that Asystasia gangetica has significant analgesic and anti-inflammatory activities in those animal models.