ANALGESIC AND ANTI-INFLAMMATORY ACTIVITY OF ETHANOLIC AND AQUEOUS LEAF EXTRACT OF TROPAEOLUM MAJUS L

Syed Mujtaba Ahmed, Anil Middha, Mohammed Omer, D. Ramakrishna

In the present study ethanolic and aqueous leaf extract of Tropaeolum majus L was investigated for analgesic and anti-inflammatory activity. Analgesic activity was determined by three different methods (tail immersion, hot plate and writhing method), anti-inflammatory activity was determined by three different methods (carrageenan, histamine induced paw edema & cotton pellet granuloma) at dose 200,400mg/kg b.wt in experimental animals using diclofenac sodium, tramadol, Indomethacin as reference drugs. In all the animals models the results obtained were statistically significant (p<0.05) in comparison to control. The results obtained indicate that Tropaeloum majus L has significant analgesic and anti-inflammatory activities in those animal models.