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An Ethnicity Based Assessment of Adverse Drug Reactions Due To Antibiotics ???Anti microbials Usage in India

Ram Krishna Prasad*, D. Satyawati, Fatima Tahniyath, P. Neehar, Narayani

To assess and evaluate the suspected ADRs reported among two ethnic groups with use of antibiotic (antimicrobials) medications. A prospective observational study was conducted over a period of approximately 2 years on inpatient population involving two ethnic groups ; Santhals and Chaush tribe attending Rajendra Institute of Medical Science (RIMS) situated in Ranchi, Jharkhand state, India and Axon hospital situated in Hyderabad, Telangana state, India. Non-statistical significance in odds for number of suspected ADRs for both ethnic groups (OR 0.99, 95% CI: 0.78 – 1.27). The study found no difference and events were preventable as per Schumocks and Thorontons criteria. Adverse drug reactions (ADRs) are an important cause of morbidity and mortality, susceptibility varies with genetic make-up, age, sex, physiology, exogenous factors, and disease state as ethnic groups are more susceptible during treatment. Here Ethnic group may act as a marker for underlying genetic or environmental differences.