A Hariom Prakash Rao*, V.T. Iswariya , V Lokeswara Babu and A Srinivasa Rao
Controlled-release systems are used to control the plasma concentration of the drug after administration by various possible routes. These are the systems in which the drug is released in a predetermined pattern over a fixed period of time. The release kinetics is usually zero-order. Ideally the release rate from the dosage form should be the ratedetermining step for the absorption of the drug and in fact for the drug concentration in the plasma and target site. The controlled release formulations will reduces the dosing frequency required for daily. This article provides an ideal requirements, advantages, properties and different approaches involved in the development of controlled release formulations for the better delivery of drugs.
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