A REVIEW ON BENZOTHIAZOLE ??? A VERSATILE SCAFFOLD IN THE FIELD OF PHARMACEUTICAL CHEMISTRY

Siddhanadham Arun Satyadev*, Yejella Rajendra Prasad, Vasudeva Rao Avupati, Koduru Aparna, Manjula Jyotshana Rudru

Heterocyclic chemistry is an integral part of synthetic chemistry which finds its use as one of the major parts in pharmaceutical chemistry as useful biological entities and improved pharmacological properties. Benzothiazoles are versatile bicyclic compounds with diversified pharmacological activities and their analogues are known for their incredible structural diversity. There is a wide scope for research in areas of synthetic, pharmaceutical chemistry and medical field. The objectives of the study mainly have a hawk eye over different common routes of synthesis and cyclization procedures followed and to have a light on diversified pharmacological importance of this potent moiety. Benzothiazoles have clinical effectiveness as potential anticancer, antiinflammatory, antibacterial, antifungal. analgesic, anti-HIV, antioxidant, anticonvulsant, antitubercular, antidiabetic, and other medicinal agents.