A Clinical Study of Majoon Ushba and Marhame Safeda Kafoori in the Management of Daus Sadaf (Psoriasis)

Ashfaque Ahmad, Farzana Khatoon, Badrudduja Khan, Mohammad Mohsin

Psoriasis is a Greek word derived from “so-ri-a-sis” means itching while Daus Sadaf is an Arabic word derived from “Da” means “disease” and “Al-Sadaf” means “molluscum shells” (seep). It was considered as Taqash’shur-e-Jild (Ichthyosis) by Unani physicians. Aims and Objectives: To assess the efficacy of Majoon Ushba and Marhame Safeda-Kafoori in the management of psoriasis. Material & Methods: All the patients were given Majoon Ushba 5 gm twice daily for systemic administration and Marhame Safeda Kafoori for local application twice a day. The duration of therapy was 90 days with 6 visits at every 15 days. The assessment of efficacy was based on subjective and objective parameters. In subjective parameters symptoms included Itching, Erythema, Scaling and Induration etc., while the objective parameters included Psoriasis Area Severity Index (PASI) scale and Pictures of lesions. The data of clinical and laboratory findings were analyzed by using Paired “t” test. Result: The mean value of PASI score at the time of commencement of study was 24.15±14.44 which decreased significantly to 4.73±4.73 (p<0,001) indicating a significant antipsoriatic effect produced by the test drug. Conclusion: Based on the findings it can be concluded that Unani drugs, Majoon Ushba and Marham-e-Safeda Kafoori possess significant antipsoriatic effect and can be used in the management of Psoriasis.