EVALUATION OF ANTI-BACTERIAL ACTIVITY OF PLANT SESBANIA SESBAN Kumar Sandeep, Bajwa Baljinder Singh and Kumar Narinder The genus Sesbania sesban contains about 50 spieces, the majority of which are annuals. The greatest spieces diversity occurs in Africa with 33 spieces. The spieces Sesbania sesban belongs to sub-family Papilionoidea of the family Leguminosae. It is a small perennial tree with woody stems, yellow flowers and linear pods . Sesbania sesban is very common throughout Africa and in asian countries like India, Malaysia, Indonesia and Phillipines. Campesterol, ß-sitosterol, Cyanidine, Delphinidin glycosides, a-Keto glutaric, Oxaloacetic and     pyruvic acids, Oleanolic acid, saponins, Palmitic acid, Stearic acid, Oleic acid, Linoleic acid and Linolenic acid are reported in Whole plant. Cyanidin and Delphinidin glycosides, Flavonols are reported in flowers. The plant has been reported to possess various activities such as anti-inflammatory activity, antinociceptive activity, antidiabetic activity, antifertility activity and antioxidant activity. The present study was designed to study the anti-bacterial activity of Sesbania sesban. The extracts of Sesbania sesban stem were prepared. Soxhlet extraction was carried out by petroleum ether (60-80°C), chloroform, hexane, methanol, ethanol and then distilled water. Plant is subjected to antimicrobial study. Chloroform and methanol extracts of stem of Sesbania sesban at a concentration of 25 mg/ml were equally inhibit P. aeruginosa after 48 hrs. Both chloroform and methanol extracts at a concentration of 100 mg/ml were more effective against B. subtilis than other two bacterial strains after 48 hrs. No antibacterial activity was observed for pet ether ethanol and water extracts in a range from 25 mg/ml to 100 mg/ml. International Journal Of Pharmacy 2249-1848 2014-02-20 1 386-396 Copyright (c) Pharma Scholars. All rights reserved 2013