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|Title||Prevalence and Associated Host Factors of Candiduria and Bacteriuria among Diabetic Patients Assessment of Antimicrobial Susceptibility Patterns of Isolated Bacterial Isolates|
Introduction: Antimicrobial resistance among uropathogens causing commonly acquired UTIs is increasing. Identifying risk factors for resistance and knowing the current pattern in prevalence in the local context are important steps in choosing an appropriate therapeutic agent. Coupled with a paucity of local context data on the occurrence of candiduria among diabetic patients in Zimbabwe, the study sought to avail more information on this subject. Methodology: A laboratory based cross-sectional study was used on a sample 245 diabetic patients attending out-patients’ diabetic clinic at a referral hospital in Harare, Zimbabwe. Results: The prevalence of bacteriuria was 22.9% with no statistical difference between males and females (p = 0.051). The prevalence of candiduria was 13.5% with statistical difference between males and females (p = 0.042). Gentamycin and Nicene were effective against most bacterial isolates obtained. There was a marked increase in the incidence of bacteriuria and candiduria in the unemployed (25,8% and 16,1% respectively) than in employed individuals (13,6% and 5,1% respectively). Conclusion: High resistance rates exhibited to some commonly used antimicrobials may mean the continued use of these antibiotics when considering therapy for bacteriuria seems to be under threat. Additional surveillance data that combines results of in-vitro susceptibility tests with epidemiologic and clinical patient characteristics is needed.